“As a nature lover and a food lover, I can also spend the whole day in a library.”

11971008[at]zju.edu.cn

PhD student (2nd yr)

My main research interests cover bacteriophage, bacteria, and the human immune system. Specifically, I am interested in how the bacteriophages benefit bacterial life, such as phage and antibiotic resistance, motility, adhesion, and quorum sensing. And whether these benefits can extent to human diseases or whether they have any effects on the human immune responses. My current project is focused on the structure of the filamentous phage coat proteins, and their function during the infection process.

Education

2019 – present

Zhejiang University, China
PhD in Molecular Biology & Biochemistry
A. Prof. Sebastian Leptihn

2010 – 2013

Zunyi Medical University, China
Masters in Medicine
Prof. XinSheng Yao

2005 – 2010

Shenyang Medical College, China
Bachelor of Medicine

Work Experience

2013 – 2019

Zunyi Medical University, China
Lecturer

Publications

Loh B, Wang X, Hua X, Chook HW, Ma L, Zhang L, Manohar P, Jin Y, Leptihn S. (2021). Complete Genome of the Lytic Bacteriophage Phab24 that infects Clinical Strains of the Nosocomial Pathogen Acinetobacter baumannii. Microbiology Resource Announcements. 10(40) e00669-21.

Li, Y., Ma, L., Dong, X., Pan, Y., Shi, B., He, X., Zhang, T., Sun, S., and Yao, X. (2019). Preliminary analysis of spatial-temporal homogeneity and heterogeneity of TCR beta chain CDR3 repertoires in BALB/c mice. Int J Mol Epidemiol Genet 10, 10-28.

Shi, B., Ma, L., He, X., Wu, P., Wang, P., Wang, X., Ma, R., and Yao, X. (2018). Compositional characteristics of human peripheral TRBV pseudogene rearrangements. Scientific reports 8, 5926.

Ma, L., Wang, X., Bi, X., Yang, J., Shi, B., He, X., Ma, R., Ma, Q., and Yao, X. (2017). Characteristics Peripheral Blood IgG and IgM Heavy Chain Complementarity Determining Region 3 Repertoire before and after Immunization with Recombinant HBV Vaccine. PloS one 12, e0170479.

Yu, J., Shi, B., Ma, L., Liu, C., Sun, S., Ma, R., Qiu, Y., and Yao, X. (2017). Case report for recurrent and new-onset SLE patients treated by high-dose glucocorticoid therapy: Characteristics of peripheral TCR beta chain CDR3 repertoires. Medicine 96, e9022.

Ma, L., Yang, L., Bin, S., He, X., Peng, A., Li, Y., Zhang, T., Sun, S., Ma, R., and Yao, X. (2016). Analyzing the CDR3 Repertoire with respect to TCR-Beta Chain V-D-J and V-J Rearrangements in Peripheral T Cells using HTS. Scientific reports 6, 29544.

Shi, B., Yu, J., Ma, L., Ma, Q., Liu, C., Sun, S., Ma, R., and Yao, X. (2016). Short-term assessment of BCR repertoires of SLE patients after high dose glucocorticoid therapy with high-throughput sequencing. SpringerPlus 5, 75.

Li, Z., Long, M., ChunMei, L., Bin, S., Jiang, Y., Rui, M., Qingqing, M., and XinSheng, Y. (2015). Composition and variation analysis of TCR beta-chain CDR3 repertoire in the thymus and spleen of MRL/lpr mouse at different ages. Immunogenetics 67, 25-37.

Shi, B., Ma, L., He, X., Wang, X., Wang, P., Zhou, L., and Yao, X. (2014). Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST. Theoretical biology & medical modelling 11, 30.